Aging is characterized by several key biological processes, often referred to as the hallmarks of aging. These include mitochondrial dysfunction, a decline in macroautophagy (i.e., mitophagy), cellular senescence, and chronic inflammation, amongst others. Addressing these hallmarks is crucial for promoting longevity and improving quality of life as we age. Urolithin A, a gut-derived metabolite, has emerged as a promising compound in the field of longevity due to its ability to directly influence several key longevity pathways. Over 15 years of research have demonstrated its ability to enhance mitochondrial function through the process of mitophagy, resulting in improved cellular energy and declining levels of inflammatory markers. Several rigorous randomized controlled trials (RCTs) have demonstrated how Urolithin A's molecular and cellular effects improve the function of several organs and systems within the body, including muscle, immune, and skin health, highlighting its potential as a key player in the fight against age-related decline. This presentation will delve into the latest research on Urolithin A, exploring its mechanisms of action and its role as an innovative strategy for promoting healthy aging. By the end of this session, attendees will gain valuable insights into the benefits of Urolithin A and how to utilize it in clinical practice.
Learning Objective #1: Understand how Urolithin A influences key longevity pathways, particularly its role in enhancing mitochondrial function through mitophagy and reducing inflammatory and senescence markers.
Learning Objective #2: Evaluate the clinical evidence from recent randomized controlled trials (RCTs) on Urolithin A’s impact on muscle, immune, and skin health.
Learning Objective #3: Consider practical applications of utilizing Urolithin A, highlighting how to safely choose a dietary supplement.
Jennifer is a seasoned Registered Dietitian Nutritionist with over two decades of expertise in nutrition and wellness. During her career, she has worked at some of the nation’s leading health and wellness institutions, showcasing her depth of experience in the field. Jen’s master’s degree in Integrative and Functional Nutrition, coupled with advanced training in bioenergetics and hormone health, provides her with a profound understanding of the complex interplay between nutrition, cellular health, and longevity. This specialized education has equipped Jen with a unique skill set, enabling her to delve into the nuances of how dietary and lifestyle factors influence the body’s energy production and biological processes of aging. Jen is currently the Senior Manager of Nutrition Affairs of Timeline Nutrition, where she plays a pivotal role in educating both healthcare professionals and consumers about the significance of cellular health and Urolithin A in the context of aging and longevity. Beyond her responsibilities at Timeline, she is a renowned speaker, writer, and media figure. Jennifer also continues to practice as a nutrition coach, dedicating herself to assisting clients in optimizing their nutrition for enhanced vitality and a longer healthspan.
Dr. Poonam Desai is a double board-certified and double fellowship-trained physician specializing in Lifestyle Medicine. A renowned celebrity physician, TEDx speaker, and founder of Longevity Place, Dr. Desai leads a premier clinic in New York that integrates cutting-edge science with personalized medicine to optimize health and promote longevity. Her interests span gut health, hormone health, and toxin-free living, offering concierge-level care tailored to each individual.
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