Metabolic dysfunction mechanistically underpins the array of chronic degenerative conditions that the World Health Organization now ranks as the leading causes of death worldwide. Exciting new research reveals that uric acid, previously considered clinically relevant only in the context of gout or kidney stones, actually plays a central role in regulating insulin sensitivity, metabolism, blood pressure and lipid balance. As such, understanding the factors that increase uric acid levels as well supported lifestyle interventions designed to normalize uric acid values presents a new and powerful adjunctive clinical tool for the overall health and wellbeing of patients.
Learning Objectives:
- Summarize the history of the human uricase deficiency
- Review uric acid metabolism and the important role of fructose consumption in uric acid elevation
- Recognize the relationship between elevation of uric acid and overall health and wellbeing
- List how to implement specific lifestyle and nutritional interventions to bring about normalization of uric acid levels
