Emily Stein, Ph.D. is co-founder and CEO of Primal Health LLC, a Life Sciences company aiming to revolutionize oral and systemic health through the development of novel oral microbiome modulatory products, with a current focus on the root cause of biofilm-related oral diseases. She brings a deep understanding of the intricacies of the bacterial-human interface to preventative healthcare.
Dr. Stein has been involved at the ground-level in five biotech start-ups spanning sympathetic nervous system overdrive, infectious disease diagnostics, cancer diagnostics, pulmonary fibrosis and periodontal disease. She is the inventor of 18 issued patents and has given over 25 international lectures and has received numerous awards. Dr. Stein is one of the leading scientists in the oral microbiome and soft tissue inflammation.
Dr. Stein has learned in the trenches on how to build lean start-ups and drive value through achieving clinical outcomes. Her experiences have taught her that: (i) considering patient needs in every decision, and (ii) building a passionate and driven start-up team are pivotal for success. Moreover, in order to build commercially-viable solutions to problems that plague the healthcare industry, an omni-channel approach with numerous stakeholders is needed along the way.
Dr. Stein completed her Post-Doctoral Fellowship in the Department of Immunology & Rheumatology at Stanford University School of Medicine, where she studied the role of the neuroendocrine-immune axis in rheumatoid arthritis and other autoimmune diseases. There, she studied endogenous cardiogenic steroids and their role in autoimmune inflammation, as well as developed a small molecule approach to stimulate regulatory B cells, thus downregulating autoantibody production. Her work led to a cost-effective treatment for myasthenia gravis that is used today in low-income countries.
Dr. Stein holds a PhD in Microbiology from the University of California at Berkeley where she studied serine/threonine and tyrosine kinase-dependent signaling pathways that are involved in nutrient sensing and stress response pathways in bacteria and biofilm development. Dr. Stein received a B.A. in Anthropology and a B.S. in Microbiology and Immunology at the University of Iowa where she studied the interaction between M. tuberculosis and alveolar macrophage.