The Amazonian annatto plant has existed for centuries, with archaeological findings pointing to its use by ancient civilizations as early as 3,600 BCE. Also referred to as the “lipstick plant”, annatto contains a pigment that is utilized as coloring for foods and cosmetics. Annatto was discovered to contain tocotrienol and geranylgeraniol, two phytonutrients with considerable anti-aging benefits.

This presentation examines clinically relevant data of tocotrienol’s anti-oxidant and anti-inflammatory properties in cardiometabolic disease and NAFLD, cellular health, and the aging bone. Also introduced will be annatto-derived geranylgeraniol, an endogenous nutrient the body uses to synthesize CoQ10, vitamin K, testosterone, and proteins.

Learning Objectives:

1.      Differentiate between vitamin E isomers and sources

2.      Identify current clinical trials on tocotrienols

3.      Apply clinical knowledge of tocotrienol benefits relevant to healthy aging (e.g. cardiometabolic, liver, bone, and cellular health)

4.      Recognize geranylgeraniol as an important anti-aging endogenous nutrient

5.      Recommend appropriate dosages for practitioners and consumers